Abiraterone acetate is a medication used in the treatment of advanced prostate cancer. It is commonly sold under the brand name Zytiga. Abiraterone acetate is often prescribed in combination with prednisone. The combination is used to treat metastatic castration-resistant prostate cancer, which is a form of prostate cancer that has spread to other parts of the body and is resistant to hormone therapy.
Here are some key points about Abiraterone acetate:
Mechanism of Action: Abiraterone acetate inhibits an enzyme called CYP17, which plays a role in the production of androgens (male hormones). By inhibiting this enzyme, the medication helps reduce the production of androgens, which can fuel the growth of prostate cancer cells.
Indications: Abiraterone acetate is typically prescribed for use in combination with prednisone for the treatment of metastatic castration-resistant prostate cancer.
Dosage: The dosage of Abiraterone acetate can vary, and it is important to follow the prescribed regimen provided by a healthcare professional.
Side Effects: Common side effects may include fatigue, joint swelling or pain, hot flashes, hypertension, and fluid retention. It's important to report any unusual or severe side effects to a healthcare provider.
Administration: Abiraterone acetate is usually taken on an empty stomach, either one hour before or two hours after a meal. Prednisone is typically taken alongside Abiraterone acetate as prescribed.